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CIC Prep

Isolation precautions

Standard Precautions

Standard Precautions are the minimum infection prevention practices for every patient in every healthcare setting, whether or not an infection is suspected or confirmed. They rest on one principle: blood, body fluids, secretions, excretions (except sweat), nonintact skin and mucous membranes may all carry transmissible infectious agents.

What Standard Precautions include

  • Hand hygiene before and after patient contact, after contact with blood, body fluids or contaminated surfaces, and after removing gloves.
  • Personal protective equipment chosen by the expected exposure, not the diagnosis: gloves for blood, body fluids, mucous membranes or nonintact skin; a gown when skin or clothing may be soiled; a mask and eye protection or a face shield when splashes or sprays are likely.
  • Respiratory hygiene and cough etiquette for anyone with signs of a respiratory infection, starting at the point of entry.
  • Safe injection practices: a sterile, single-use needle and syringe for each injection.
  • A surgical mask when placing a catheter or injecting material into the spinal canal or subdural space (for example myelograms, lumbar punctures, spinal or epidural anesthesia).
  • Cleaning and reprocessing of reusable patient-care equipment, and routine cleaning and disinfection of environmental surfaces, especially those touched often.
  • Handling used textiles and laundry with minimum agitation.
  • Preventing sharps injuries, and using mouthpieces, resuscitation bags or other ventilation devices instead of mouth-to-mouth resuscitation.

Patient placement

  • No special room is required.
  • Patients who are more likely to spread infection — for example with uncontained secretions, excretions or wound drainage — should be placed in a single room when one is available.

173 of the conditions in CDC’s Appendix A need Standard Precautions only. See them in the lookup.

Test yourself: a CIC-style question

What is the cornerstone of Standard Precautions?

  1. Wearing gloves for all patient contact
  2. Treating blood and all body fluids as potentially infectious regardless of the patient’s diagnosis
  3. Isolating all patients with an unknown diagnosis
  4. Using N95 respirators for all direct patient care
Show answer

B. Treating blood and all body fluids as potentially infectious regardless of the patient’s diagnosis

Standard Precautions apply to every patient regardless of diagnosis and assume that blood, body fluids (except sweat), nonintact skin and mucous membranes may be infectious. PPE is chosen by the task and the expected exposure.

Questions like this come up in the Preventing and Controlling the Transmission of Infectious Agents domain of the CIC® exam. The 654 questions in the app each come with a written explanation.

FAQ

Who needs Standard Precautions?
Every patient, in every healthcare setting, at all times. Standard Precautions do not depend on a diagnosis; Transmission-Based Precautions (Contact, Droplet, Airborne) are added on top of them when a specific infection is known or suspected.
Is a gown always required under Standard Precautions?
No. Under Standard Precautions PPE is chosen by the expected exposure: a gown is worn when skin or clothing may contact blood, body fluids, secretions or excretions.

Sources

  1. CDC. 2007 Guideline for Isolation Precautions: Summary of Recommendations
  2. CDC. Appendix A: Type and Duration of Precautions Recommended for Selected Infections and Conditions (2007 Guideline for Isolation Precautions, updated September 2024)

Checked against CDC on October 21, 2026. For education and CIC® exam preparation only — not a substitute for your facility’s infection prevention policies, your state or local health department, or clinical judgment. CBIC and CDC do not endorse this tool.

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